This truncated sequence containing the N-terminal 24 amino acids of ACTH still exhibits corticotropic activity, but it is less immunogenic than the full-length peptide hormone. ACTH 1-24 induces an increase in the circulating level of glucocorticoids.
Sequence: H-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-Gly-Lys-Lys-Arg-Arg-Pro-Val-Lys-Val-Tyr-Pro-OH
CAS:16960-16-0
Formula: C136H210N40O31S
MW: 2933,48
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